News for 08-Aug-22
The Best scientific meetings website
All the scientific meetings information you need to know about is right
here. Presented and researched by http://www.md-news.net. We've searched
the information super highway far and wide to provide you with the
best scientific meetings site on the internet today. The links below will
assist you in your efforts to find the information that you are looking
Welcome to the Internet. Like it or lump it you'll find much more than you need. That's where we come in and provide assistance. We've done the research for you and found the very best links on scientific meetings. Our primary role in this process is to search for information on scientific meetings, evaluate it and then determine whether it is likely to meet your needs. We won't be bold enough to call ourselves scientific meetings librarians but in one sense that it what we are doing.
scientific meetings information exists in a large variety of formats and genres (facts, opinions, scientific meetings stories, interpretations and so on). This information has been created to inform, persuade and educate you on all that you ever need to know about scientific meetings. The quality ranges from poor to brilliant with lots of shades in between.
The links will take you to web sites we judge have been created by experts in the field of scientific meetings, and that will become obvious to you also as soon as you arrive at the sites. However we know that everyone is different in their scientific meetings requirements and suggest if you don't find what you are looking for at the above sites, visit Yahoo which is arguably the best search engine on the net, and then perform a search on scientific meetings.
We might mention that yahoo is by no means your only search engine option when you are looking for scientific meetings information, other search engines are google alta vista, hotbot, msn, etc which should all produce good scientific meetings results.
The Facts About Glutathione and Parkinson's Disease
by: Priya Shah
Parkinson's Disease (PD), a devastating illness, occurs in one of every 100 people over 65.
It is a slowly progressing disease of the nervous system that results in progressive destruction of brain cells (neurons) in an area of the brain called the substantia nigra. Death occurs usually as a result of secondary complications such as infection.
One of the mechanisms known to destroy neurons is damage by free radicals or reactive oxygen species - destructive molecules produced by oxidation of the neurotransmitter dopamine.
The Role of Dopamine
The cells of the substantia nigra use dopamine - a chemical messenger between brain or nerve cells - to communicate with cells in another region of the brain called the striatum.
When nigral cells are lost, nigral dopamine levels fall, resulting in a decrease in striatal dopamine.
The typical symptoms of PD - motor function deficiencies characterized by muscle rigidity, jerky movements, rhythmic resting tremors - are the result of low levels of striatal dopamine.
Most dopaminergic drugs used to treat PD, are aimed at temporarily replenishing or mimicking dopamine. They improve some symptoms, but do not restore normal brain function nor halt brain cell destruction.
Dopaminergic drugs are generally effective at first in reducing many PD symptoms, but over time they lose their effect.
They also cause severe side effects because they overstimulate nerve cells elsewhere in the body and cause confusion, hallucinations, nausea and fluctuations in the movement of limbs.
The Role of Antioxidants
When dopaminergic neurons are lost in the course of Parkinson's disease, the metabolism of dopamine is increased - which in turn increases the formation of highly neurotoxic hydroxyl radicals.
The most important free radical scavenger in the cells of the substantia nigra is the powerful brain antioxidant, glutathione. Glutathione levels in PD patients are low.
And as we age, levels of glutathione in the dopaminergic neurons of the substantia nigra decreases. This appears to hasten cell death and advance the progression of PD.
At least 80 percent of the substantia nigra cells are lost before symptoms of Parkinson's disease become apparent. This is why it becomes essential to protect or maintain these cells under oxidative stress.
How does Glutathione help in Parkinson's Disease?
Several factors explain why glutathione is so beneficial in Parkinson's disease.
1. Glutathione increases the sensitivity of the brain to dopamine. So although glutathione doesn't raise dopamine levels, it allows the dopamine in the brain to be more effective.
2. Glutathione's powerful antioxidant activity protects the brain from free radical damage.
3. An even more intriguing benefit of glutathione lies in its powerful detoxification ability.
Its a well known fact that most Parkinson's patients are deficient in their ability to detoxify chemicals to which they are exposed.
The unfortunate few who harbor an inherited flaw in their detoxification pathways are at far greater risk to the brain damaging effects of a wide variety of toxins.
Glutathione is one of the most important components of the liver's detoxification system. Glutathione therapy is one of the most effective techniques for enhancing liver and brain detoxification.
Glutathione treatments considerably improve some of the symptoms of Parkinson's disease including difficulties with rigidity, walking, movement, coordination and speech. A marked reduction of tremor has been observed as well as a decrease in depression.
Glutathione and N-acetyl-L-cysteine (a glutathione precursor) have been shown to be very effective in protecting the nerves in the substantia nigra from being destroyed by oxidative stress.
Glutathione Therapy in Parkinson's Disease
The practical problem in increasing glutathione levels is that taking glutathione itself as a supplement does not boost cellular glutathione levels, since glutathione breaks down in the digestive tract before it reaches the cells.
However, intravenous glutathione therapy and taking glutathione precursors are both effective in boosting intracellular levels of glutathione.
Intravenous Glutathione Therapy:
Intravenous glutathione injections have been shown to have amazing and quick results.
Dr. David Perlmutter, a pioneer in this therapy, has developed a protocol utilized at the Perlmutter Health Center for administering intravenous glutathione to Parkinson's patients.
Following even a single dosage of intravenous glutathione - often in as little as 15 minutes - the ability to walk, turn around and move their arms is almost completely restored.
Dietary antioxidants and supplements that increase cellular glutathione, such as alpha lipoic acid, NAC, pycnogenol, the herb silymarin (milk thistle), are effective in restoring normal function.
N-acetyl-cysteine (NAC) and un-denatured, whey protein both supply glutathione precursors intracellularly, enhance the body's production of glutathione and aid the detoxification process.
Other nutritional supplements which aid the detoxification process include selenium, vitamins E and C.
For a detailed report with references on Parkinson's Disease and Glutathione visit:
Copyright © 2004 Priya Shah
|MD Meet Real Time Media On The Net Drugestore On-the-Net|